Isabella Karle’s Interview (2005)
The daughter of Polish immigrants, Isabella Karle had received her Bachelor’s, Master’s, and PhD degrees in physical chemistry from the University of Michigan by the time she was 22 in 1943. With her husband, Jerome Karle, a fellow student and scientist whom she married in 1942, Isabella became a pioneer in the field of science, starting with her work on the Manhattan Project at the University of Chicago in 1943. After the war, Isabella and Jerome began work on crystallography at the US Naval Research Laboratory in Washington, DC, where they were employed for over sixty years until their retirement in 2009. In this interview, Isabella discusses the career path she took after high school to become a chemist. She also explains how she came to work for the Manhattan Project in 1943, how she met her husband at the University of Michigan, and the successful careers of other scientists she worked with during the Manhattan Project.